THE FACTORS RELATED TO THE EFFECTIVENESS OF CYANOACRYLATE GLUE INJECTION IN THE TREATMENT OF GASTRIC VARICEAL RUPTURE Travel Award

Aims:
Gastric varices (GV) may lead to gastrointestinal (GI) bleeding higher mortality rate than esophageal varices. Studies have shown the safety and effectiveness of cyanoacrylate glue injection in the emergency treatment of GV rupture. This study aims to determine the factors related to the effectiveness of this treatment method.
Methods:
We retrospectively reviewed the data of 48 patients who received cyanoacrylate glue injections to treat GV rupture at our hospital from 2019 to 2023. The effectiveness of the glue injection method was evaluated based on the contrast-enhanced computed tomography of the abdomen after the intervention that the glue filled the dilated bulge, the GI status was stable after the intervention and the patient did not have GI bleeding due to ruptured GV recurrence within 1 month.
Results:
The rate of effective glue injection for emergency interventions was 60.4% (29/48). In the multivariable logistic regression, the associated factors of effective glue injection for ruptured GV treatment included the time of endoscopic intervention within 24 hours of admission (OR= 7.279, 95%Cl: 1.345-39.396, p=0.021) and the Child-Turcotte-Pugh scores <= 9 (OR=16.632, 95%Cl: 1.818-152.175, p=0.013).
Conclusions:
The timing of emergency glue injection and the Child-Turcotte-Pugh classification are the prognostic factors for the effectiveness of the cyanoacrylate glue injection in the treatment of GV rupture.