Japan Digestive Disease Week 2025
International Poster Session1 (JDDW)
October 31, 9:30–10:18, Room 15 (Kobe International Exhibition Hall No.1 Building Digital Poster Venue)
IP-6_S
Endoscopic Resection versus Laparoscopic Resection for Gastric Submucosal Tumor: A Systematic Review and Meta-analysis of Safety and Efficacy
- 1
- Department of Gastrointestinal Surgery, Kanazawa University
- 2
- Department of Surgical Sciences, University of Turin
Introduction
Gastric submucosal tumors (G-SMTs) vary in malignancy risk, with surgical resection as the standard treatment. Although endoscopic resection (ER) offers a less invasive approach, its outcomes remain unclear compared to laparoscopic resection (LR). This study evaluates the safety and efficacy of ER and LR for G-SMTs.
Materials and Methods
A systematic review and meta-analysis included articles comparing ER and LR for G-SMTs. Primary outcome was complete resection rate.
Results
Nineteen studies included 673 patients in the ER group and 521 in the LR group. Analysis of the complete resection rate favored LR with RR 0.98 (95% CI 0.97-0.99, p<0.01). ER showed favor in operative time (95% CI -54.46; -24.97, p<0.01), blood loss (95% CI -55.74; -12.70, p<0.01), time to oral intake (95% CI -1.64; -0.33, p<0.01), and hospital stay (95% CI -2.18; -0.59, p<0.01). A subgroup analysis of endoscopic full-thickness resection (EFTR) vs LR showed no significant difference in complete resection rate (RR 0.98, 95% CI 0.95; 1.01, p=0.18).
Conclusions
LR may have a higher complete resection rate, but ER provides better short-term outcomes. Full-thickness resection, when performed, achieved a comparable resection rate to LR, suggesting potential for broader adoption with further technical advancements.
Gastric submucosal tumors (G-SMTs) vary in malignancy risk, with surgical resection as the standard treatment. Although endoscopic resection (ER) offers a less invasive approach, its outcomes remain unclear compared to laparoscopic resection (LR). This study evaluates the safety and efficacy of ER and LR for G-SMTs.
Materials and Methods
A systematic review and meta-analysis included articles comparing ER and LR for G-SMTs. Primary outcome was complete resection rate.
Results
Nineteen studies included 673 patients in the ER group and 521 in the LR group. Analysis of the complete resection rate favored LR with RR 0.98 (95% CI 0.97-0.99, p<0.01). ER showed favor in operative time (95% CI -54.46; -24.97, p<0.01), blood loss (95% CI -55.74; -12.70, p<0.01), time to oral intake (95% CI -1.64; -0.33, p<0.01), and hospital stay (95% CI -2.18; -0.59, p<0.01). A subgroup analysis of endoscopic full-thickness resection (EFTR) vs LR showed no significant difference in complete resection rate (RR 0.98, 95% CI 0.95; 1.01, p=0.18).
Conclusions
LR may have a higher complete resection rate, but ER provides better short-term outcomes. Full-thickness resection, when performed, achieved a comparable resection rate to LR, suggesting potential for broader adoption with further technical advancements.
- Index Term 1: Gastric submucosal tumor
- Index Term 2: Meta-analysis