Strategic International Session3(JSGS・JSGE・JSH)
Sat. November 4th   9:00 - 11:30   Room 9: Portopia Hotel Main Building Kairaku 3
ST3-Keynote Lecture
Current status and prospects of liver transplantation for cholangiocarcinoma or metastatic liver cancer
Gonzalo Sapisochin
University of Toronto
Transplant Oncology is a revisited discipline within organ transplantation that includes liver transplantation for malignancies. With improvements of the outcomes of liver transplantation and oncological management of patients with hepatobiliary malignancies such as metastatic colorectal cancer to the liver and cholangiocarcinoma, transplant oncology is becoming one of the main indications for liver transplantation.
Patients with hilar and intrahepatic cholangiocarcinoma have been shown to benefit from a total hepatectomy followed by liver transplant after showing stability on systemic and locoregional treatments. Several trials are ongoing in this space.
With regards to patients with metastatic colorectal cancer to the liver, in the last decade there has been evidence that for selected patients, the 5-year survival can be up to 70-80% after transplantation. Several trials are on their way around the globe, and many centers are demonstrating that liver transplantation in the setting on liver-only disease can achieve survival benefit.
This lecture will summarize the main concepts of transplant oncology and the future perspectives of this discipline. It will also focus on the recent advancements in liver transplantation for cholangiocarcinoma and metastatic colorectal cancer to the liver.
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