International Session(Workshop)3(JGES・JSGE・JSGS・JSGCS)
Sat. November 4th   14:00 - 16:30   Room 11: Portopia Hotel South Wing Topaz
Randomized controlled trial comparing conventional and traction endoscopic submucosal dissection for early colon tumor (CONNECT-C trial)
Ryoji Ichijima1, Daiki Nemoto2, Hisatomo Ikehara1,3
1Division of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of Medicine, 2Department of Coloproctology, Fukushima Medical University Aizu Medical Center, 3Department of Gastroenterology, Kitasato University School of Medicine
Endoscopic submucosal dissection (ESD) is a widely accepted treatment. Some previous studies have shown the usefulness of the traction method on colon ESD. However, these studies used a small sample, single-center design. We thus aimed to investigate the efficacy and safety of the traction method in colon ESD.
Methods: We conducted a prospective, multicenter, randomized, two-arm controlled trial at 10 facilities in Japan. A 1:1 allocation was conducted for the conventional ESD (C-ESD) and traction ESD (T-ESD) groups.
Results: We included 128 C-ESD and 123 T-ESD cases. The median procedure times for C-ESD and T-ESD were 61 (40-100) and 53 (40-76) min (P = 0.18), respectively, and no significant differences were observed between the groups. Subgroup analysis showed that the median procedure times for patients with a lesion diameter of >30 mm in the C-ESD and T-ESD groups were 89 (57-80) and 69 (50-104) min (P=0.05), respectively, and for nonexpert operators were 81 (62-120) and 64 (52-109) min (P=0.07), respectively.
Conclusions: The traction method did not contribute to a significantly shortened ESD procedure time. However, this method may be useful when the tumor diameter is large or if the procedure is conducted by nonexpert endoscopists.
Index Term 1: colon ESD
Index Term 2: traction
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