International Session(Symposium)1(JSH・JSGE・JSGCS)
Fri. November 3rd   14:30 - 17:00   Room 9: Portopia Hotel Main Building Kairaku 3
Current status of liver transplantation for HCC after the transition of indication for transplantation
Kaori Kuramitsu1, Shohei Komatsu1, Takumi Fukumoto1
1Department of Surgery, Division of Hepato-Biliary-Pancreatic Surgery, Kobe University Graduate School of Medicine
Backgrounds; After the transition of indication for transplantation, MELD score for HCC patients reaches up to 25 in 2020. Accordingly, the percentage of HCC patients for DDLT is expected to increase.
Methods; 58 cases which was performed liver transplantation from 2009 to 2018 and 511 cases which was performed primary hepatectomy for HCC during the same period was analyzed in the present study. The patients were categorized into two groups; early (~2013) and late (2014~) period.
Results; During early period, 14/27 cases were HCV patients while 3/31 in late period. HCC was identified only in early period. 1-year survival was not affected by the existence of HCC (P=0.31). 100/245 patients were HCV patients during early period while 97/272 in late period. NASH patients increased from 38.0% up to 46.3% in lated period. HCC stage I/II increased from 40.4% up to 56.3% in late period (P=0.0003) and partial hepatectomy increased from 24.5% up to 36.4% (P=0.0002). Background fibrosis stage did not change by period. OS by period did not change with statistical difference.
Discussion; As the percentage of HCC for transplantation is expected to increase, background disease treatment for NASH is essential for longer survival after transplantation.
Index Term 1: liver transplantation
Index Term 2: HCC
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