Japan Digestive Disease Week 2022
International Session (Workshop)1 (JGES, JSGE, JSH, JSGS)
October 28, 14:30–17:00, Room 9 (Fukuoka International Congress Center 413+414)
IS-W1-5_E
The role of direct peroral cholangioscopy for the detection of intraductal neoplasms of the bile duct Travel Award
- 1
- Digestive Disease Center and Research Institute, Department of Internal Medicine, SoonChunHyang University School of Medicine
Background and Aims: Since indirect diagnostic modalities have been unsatisfactory for detecting intraductal neoplasms of the bile duct (IN-B), direct peroral cholangioscopy (POC) using an ultraslim endoscope can be a possible alternative. Here, we evaluated the efficacy of direct POC for the detection of IN-B.
Methods: Consecutive 471 patients who underwent direct POC were enrolled between April 2008 and July 2020. Intraductal superficial lesions of the bile duct (ISL-B) were investigated under POC using narrow-band imaging (NBI), and correlated to histologic findings after POC guided forceps biopsy (POC-FB) or surgery. The detection rate of IN-B, technical success of POC and POC-FB, and adverse events were analyzed.
Results: Direct POC was successful in 458 of 471 patients (97.2%). Mild cholangitis developed in 4 patients (0.8%), which was resolved conservatively. Of the 458 successfully performed POCs, 133 patients (29.0%) exhibited ISL-B. The technical success of POC-FB was 94.0% (125/133). Of the 125 successfully performed POC-FBs, 41.6% (52/125) exhibited IN-B. Curative-intent surgery was performed in 21/52 (40.4%) patients with IN-B.
Conclusions: Direct POC using an ultraslim endoscope with NBI is useful for the detection of IN-B.
Methods: Consecutive 471 patients who underwent direct POC were enrolled between April 2008 and July 2020. Intraductal superficial lesions of the bile duct (ISL-B) were investigated under POC using narrow-band imaging (NBI), and correlated to histologic findings after POC guided forceps biopsy (POC-FB) or surgery. The detection rate of IN-B, technical success of POC and POC-FB, and adverse events were analyzed.
Results: Direct POC was successful in 458 of 471 patients (97.2%). Mild cholangitis developed in 4 patients (0.8%), which was resolved conservatively. Of the 458 successfully performed POCs, 133 patients (29.0%) exhibited ISL-B. The technical success of POC-FB was 94.0% (125/133). Of the 125 successfully performed POC-FBs, 41.6% (52/125) exhibited IN-B. Curative-intent surgery was performed in 21/52 (40.4%) patients with IN-B.
Conclusions: Direct POC using an ultraslim endoscope with NBI is useful for the detection of IN-B.
- Index Term 1: intraductal neoplasms of bile duct
- Index Term 2: peroral cholangioscopy