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International Session(Symposium)7(JSGS・JSGE・JGES)
Sat. November 23rd   10:00 - 12:00   Room 1: Kobe International Exhibition Hall No.2 Building Hall (North)
IS-S7-6_S
The current status of postoperative anastomotic ulcers in patients with Crohn’s disease: Japanese multi-center nationwide cohort study
Takeshi Ueda1, Hisao Fujii2, Fumikazu Koyama3
1Department of Surgery, Minami-Nara General Medical Center, 2Gastrointestinal Endoscopy and IBD Center, Yoshida Hospital, 3Division of Endoscopy, Nara Medical University Hospital
Background: The most frequent postoperative lesions in Crohn’s disease are on peri-anastomotic site. In this study, we showed the current status of postoperative peri-anastomotic lesions, and discussed that these lesions especially linear ulcers on anastomosis, were recurrence or not.
Methods: We conducted a retrospective, observational, multicenter study that included 18 institutions in Japan. Patients who underwent intestinal resection between 2008 and 2013 and observed peri-anastomotic site endoscopically were included. The details of postoperative peri-anastomotic lesions were reviewed.
Result: There were 267 cases with the first time endoscopic findings (first analysis) and 178 with more than 2 times endoscopic examinations (second analysis). In the first analysis, there were 124 with ulcers on the anastomosis and 101 with near anastomotic ulcers. The peri-anastomotic lesions were detected in 163 (61.0%). There were no significant factors on arising lesions except including ileum in anastomosis. In the second analysis, the peri-anastomotic lesions increased and mucosal healing rate decreased to 19.7%. The patients with linear ulcers on the anastomotic line had same ulcers continuously at 61.5% (16/26 cases).
Conclusion: It is highly possible that the linear ulcers on the anastomotic line are not recurrent lesions. It is necessary to define detail classifications of postoperative anastomotic lesions from Japan performing careful endoscopic observations.
Index Term 1: anastomotic ulcer
Index Term 2: peri-operative lesion
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