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International Session(Symposium)7(JSGS・JSGE・JGES)
Sat. November 23rd   10:00 - 12:00   Room 1: Kobe International Exhibition Hall No.2 Building Hall (North)
IS-S7-4_S
Clinical results following intestinal resection in 1143 patients with Crohn's disease
Ryuichi Kuwahara1, Hiroki Ikeuchi1, Motoi Uchino1
1Department of Inflammatory Bowel Disease Surgery, Hyogo College of Medicine
(Objectives)
Crohn's disease (CD) is an intractable inflammatory bowel disease of unknown cause that shows repeated recurrence and occasionally requires multiple surgical procedures. We examined clinical features and the postoperative course of 1143 patients who underwent intestinal resection for CD at our hospital.
(Methods)
From September 1974 to July 2014, 1143 patients underwent a total of 2001 intestinal resection procedures for CD at our hospital.
(Results)
There were 827 males and 316 females, for a ratio of 2.6:1. Mean age at the initial surgery was 30.0 years (range 7-78 years) and the duration of disease was 20.4 years (2.5-43.2 years). Postoperative complications (Clavien-Dindo III and above) were confirmed in 66 cases (3.3%), with leakage the most frequent (n=45, 2.2%).
The cumulative 5-year reoperation rate was 22.2%. The recurrence was 235 in the anastomotic site, 197 in the other site, 51 in both cases. Presence of an anal lesion at the initial surgery was a significant factor related to reoperation (p=0.001). At the time of the analysis, 24 (2.1%) patients had died, 16 of which were cancer deaths.
(Conclusions)
The reoperation rate for the cumulative 5-year period was 22.2% and the only risk factor for another surgery found was presence of an anal lesion at the initial surgery.
Index Term 1: Crohn's disease
Index Term 2: reoperation rate
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