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Invited Lecture International Session
(Symposium) International Session
(Workshop) Symposium Workshop International Poster Session
International Session（Symposium）4(JSGE・JGES)
Fri. November 22nd   9:30 - 12:00   Room 11: Portopia Hotel South Wing Topaz
IS-S4-4_G
 Classifying Functional Dyspepsia Using a Novel Drinking-Ultrasonography Test
Momoko Tsuda1, Mototsugu Kato2, Naoya Sakamoto3
1Division of Endoscopy, Hokkaido University Hospital, 2Department of Gastroenterology, National Hospital Organization Hakodate Hospital, 3Department of Gastroenterology and Hepatology, Faculty of Medicine, Hokkaido University
Background
Functional dyspepsia (FD) contains various pathophysiology. We invented drinking-ultrasonography test combining a drink test with ultrasonography to examine gastric motility and sensory function. To evaluate pathophysiological condition of FD, we classified FD patients into four groups using a drinking-ultrasonography test.
Methods
156 FD patients according to the Rome 3 or 4 were enrolled between May 2010 and October 2018. The patients drank 200ml water in 2 minutes interval for 4 times (total 800ml). The maximum cross section of the proximal stomach was visualized four times at each water intake and after 5 and 10 minutes from water intake. Abdominal sensory was assessed using visual analog scale (VAS). We then evaluated 27 FD patients who had done drinking-ultrasonography test before and after medications.
Results
The test classified FD patients into four groups, normal group (30%), impaired relaxation group (10%), delayed emptying group (3%), visceral hypersensitivity group (57%). Among 27 repeat-tested patients, 4 (14.8%) were H. pylori-associated dyspepsia patients (HPD). HPD patients improved sensory function after successful eradication whereas FD patients did not improve their sensory function even their clinical symptoms improved (p<0.01).
Conclusion
The drinking-ultrasonography test we developed identified and successfully classified pathophysiological condition of FD patients. HPD patients improve their symptoms and pathophysiological features on the contrary to FD patients.
Index Term 1: drinking-ultrasonography test
Index Term 2: Functional dyspepsia
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