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International Session (Symposium) 2 (JSH・JSGE)
Thu. November 1st   14:40 - 17:00   Room 13: Kobe International Conference Center International Conference Room
IS-S2-2_H
Epidemiology of hepatitis B virus in Japan and Asia
Junko Tanaka
Department of Epidemiology, Infectious Disease Control and Prevention, Hiroshima University
Aim: Hepatitis B prevalence is highest in the WHO WPRO and the African Region, where 6.2% and 6.1% respectively. This study aim is to compare prevalence of HBV among adult in Vietnam, general population in Siem Reap, children and their mothers in Cambodia, and Japanese employee.

Methods: The study subject were 1) 2,520 children who aged 5-7yeats and their 2,026 mothers who were selected by multi-stage stratified random sampling in all Cambodia, 2) 509 adults who were sampled using a multi-stage stratified random sampling in Binh Thuan, 3) 868 general population in Siem Reap, Cambodia, and 4) 3015 employees in Hiroshima, Japan.

Results: 1) The prevalence of HBsAg among children and mothers in Cambodia were 0.56% and 4.39%. 2) The prevalence of HBsAg, anti-HBs and anti-HBc in Binh Thuan were 15.3%, 60.3% and 71.7%, respectively. 3) The prevalence of HBsAg, anti-HBs and anti-HBc in Siem Reap were 4.7%, 24.8% and 28.3%. 4) The prevalence of HBsAg among Japanese employees was 0.95%.

Conclusion: As for Cambodia, it has met the regional goal of HBsAg prevalence <1% in 2017 although there is HBV transmission from mother to child. As for Vietnam, prevalence of HBV infections are high, genotype B is predominant, and horizontal HBV transmission may still occur. Therefore, raising the coverage of a universal HBV vaccination program may be an effective liver cancer control in Vietnam. In Japan, it was considered that prevention of HBV mother-to-infant infection.
Index Term 1: Hepatitis B virus
Index Term 2: Asia
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