International Poster Session(JDDW)
November 4 (Fri.), 14:00–15:04, Room 16 (Kobe International Exhibition Hall No. 2 Building Hall (North) Digital Poster Session)
IP-52_G

Differences in presentations of hepatitis B and hepatitis C causing decompensated liver cirrhosis

M. U. Makki1
Co-authors: N. A. Jadoon2, M. Iqbal3, Z. Butt3
1
Services Hospital
2
Data Darbar Hospital
3
King Edward Medical University
Background: In Pakistan, prevalence of HBV is 2.6% and HCV is 5.3% with an overall decrease in incidence of HBV infection and an increase in HCV infection, however, the differences in their presentation and prognosis are not known. Methods: We conducted a prospective study on 325 patients who were admitted with a primary diagnosis of decompensated liver failure due to HBV or HCV at two major tertiary care hospitals . Statistical analysis was performed using SPSS version 20 and all values were considered significant at p<0.05.Results: Patients with HCV had esophageal varices (34.07 %) confirmed by endoscopy whereas, none of the patients with HBV had esophageal varices p<0.002. HBV patients most frequently had grade 0 hepatic encephalopathy (HE) (46.67%) whereas, HCV patients had grade 3 HE (38.30%); p<0.005. Peripheral edema was found to be significant amongst patients with HBV and HCV; p<0.023. Conclusion: HCV causes a higher incidence of decompensated liver cirrhosis than HBV leading to liver failure. Major manifestations are neurological with a smaller portion being related to gastrointestinal tract and edema of extremities. Being able to detect these changes promptly can halt the progress of disease. Having a primary prevention program in place will help with the future burden of disease.
Page Top